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. 2017 Dec 22;2017(12):CD011535. doi: 10.1002/14651858.CD011535.pub2

Table 4.

Ranking findings for all outcomes at class level

Class‐level interventions SUCRA PASI 90 Rank PASI 90 SUCRA SAE Rank SAE SUCRA PASI 75 Rank PASI 75 SUCRA AE Rank AE SUCRA PGA Rank PGA SUCRA QoL Rank QoL
Anti‐IL12/23 85.7 2 53.9 3 85.0 2 57.0 3 83.8 2 75.7 3
Anti‐IL17 100.0 1 21.0 8 99.6 1 14.1 6 99.9 1 95.4 1
Anti‐IL23 71.3 3 39.6 5 72.2 3 78.7 2 73.1 3 83.4 2
Anti‐TNF alpha 56.4 4 39.2 6 57.4 4 47.5 5 57.5 4 58.4 4
Other biologics 26.3 6 68.2 2 17.0 7 _ _ 16.6 7 15.5 7
Small molecules 41.5 5 45.4 4 42.7 5 7.9 7 42.0 5 40.4 5
Conventional systemic
treatments
18.7 7 94.8 1 26.0 6 50.8 4 27.1 6 30.8 6
Placebo 0 8 38.0 7 0 8 94.0 1 0 8 0.4 8

AE: adverse events; FAEs: fumaric acid esters; PGA: Physician Global Assessment; QoL: Specific quality of life scale; SAE: serious adverse events