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. 2015 Jun 30;2015(6):CD010037. doi: 10.1002/14651858.CD010037.pub2
Methods Randomised, double‐blind clinical trial. The trial was conducted in Iran.
Participants 49 overweight men (BMI > 25 kg/m² , BMI = 27.5 ± 1.7)
Age: 34.4 ± 4.8 years.
Interventions Intervention group: carbonate calcium (1250 mg elemental calcium daily)
Control group: Placebo.
Trial duration: 8 weeks.
Outcomes Blood pressure
Serum lipid profile
Notes Diet was assess with a 24‐hour dietary recall questionnaires at baseline, 4th week, and end of the study.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Participants were divided randomly (by random number tables) into case and placebo groups
Allocation concealment (selection bias) Unclear risk Not described
Blinding of participants and personnel (performance bias) All outcomes Unclear risk Double‐blind clinical trial
Blinding of outcome assessment (detection bias) All outcomes Unclear risk Not described
Incomplete outcome data (attrition bias) All outcomes Low risk 4 participants used low‐calorie diets and we had to exclude them from the study (fewer than 10%)
Selective reporting (reporting bias) Low risk All outcomes were reported
Other bias Low risk Baseline characteristics were similar between the 2 groups