Thomsen 1987

Methods	Double‐blind randomised placebo‐controlled trial. The trial was conducted in Denmark.
Participants	28 healthy women with early menopause (6 months to 3 years earlier). Overweight was not an exclusion criterion.
Interventions	Intervention group:2000 mg calcium per day (14 participants). Control group: identical‐looking placebo tablets (14 participants). Trial duration: 1 year.
Outcomes	Blood pressure. BP was measured by mercury manometer after 10 min of supine rest
Notes	Tablets were provided by Sandoz
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Participants were allocated into 2 groups according to random sampling numbers
Allocation concealment (selection bias)	Unclear risk	Not described
Blinding of participants and personnel (performance bias) All outcomes	Low risk	Double‐blind, placebo‐controlled trial. Participants received identical‐looking tablets
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Not described
Incomplete outcome data (attrition bias) All outcomes	Low risk	All participants were evaluated at the end of the study.
Selective reporting (reporting bias)	Low risk	The primary outcome was reported.
Other bias	High risk	Placebo participants had higher initial weight and lower systolic blood pressure.