Comparison 2. Anti‐adhesion therapy A versus anti‐adhesion therapy B following operative hysteroscopy.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Live birth	3	180	Odds Ratio (M‐H, Fixed, 95% CI)	1.48 [0.57, 3.83]
1.1 Device + graft vs device	3	180	Odds Ratio (M‐H, Fixed, 95% CI)	1.48 [0.57, 3.83]
2 Clinical pregnancy	4	221	Odds Ratio (M‐H, Fixed, 95% CI)	1.72 [0.89, 3.33]
2.1 Device + graft vs device	3	180	Odds Ratio (M‐H, Fixed, 95% CI)	1.53 [0.74, 3.18]
2.2 Gel + hormone tx (HT) + antibiotics vs HT + antibiotics	1	41	Odds Ratio (M‐H, Fixed, 95% CI)	2.83 [0.62, 13.04]
3 Miscarriage	3	40	Odds Ratio (M‐H, Fixed, 95% CI)	0.80 [0.20, 3.19]
3.1 Device + graft vs device	3	40	Odds Ratio (M‐H, Fixed, 95% CI)	0.80 [0.20, 3.19]
4 Presence of intrauterine adhesions at second‐look hysteroscopy	5	451	Odds Ratio (M‐H, Fixed, 95% CI)	0.55 [0.36, 0.83]
4.1 Device vs device	1	162	Odds Ratio (M‐H, Fixed, 95% CI)	0.81 [0.42, 1.57]
4.2 Device + graft vs device	2	137	Odds Ratio (M‐H, Fixed, 95% CI)	0.53 [0.25, 1.10]
4.3 Device + gel vs device	1	111	Odds Ratio (M‐H, Fixed, 95% CI)	0.31 [0.13, 0.76]
4.4 Gel + HT + antibiotics vs HT + antibiotics	1	41	Odds Ratio (M‐H, Fixed, 95% CI)	0.28 [0.03, 2.98]
5 Mean adhesion scores in women treated for intrauterine adhesions	3		Mean Difference (IV, Random, 95% CI)	Subtotals only
5.1 Device vs device	1	162	Mean Difference (IV, Random, 95% CI)	0.0 [‐0.68, 0.68]
5.2 Device + graft vs device	1	57	Mean Difference (IV, Random, 95% CI)	‐3.10 [‐4.17, ‐2.03]
5.3 Device + gel vs device	1	111	Mean Difference (IV, Random, 95% CI)	‐1.6 [‐2.32, ‐0.88]
6 Mild adhesions at second‐look hysteroscopy	1	111	Odds Ratio (M‐H, Fixed, 95% CI)	1.11 [0.53, 2.34]
6.1 Device + gel vs device	1	111	Odds Ratio (M‐H, Fixed, 95% CI)	1.11 [0.53, 2.34]
7 Moderate or severe adhesions at second‐look hysteroscopy	2	152	Odds Ratio (M‐H, Fixed, 95% CI)	0.25 [0.10, 0.61]
7.1 Device + gel vs device	1	111	Odds Ratio (M‐H, Fixed, 95% CI)	0.24 [0.09, 0.63]
7.2 Gel + HT + antibiotics vs HT + antibiotics	1	41	Odds Ratio (M‐H, Fixed, 95% CI)	0.28 [0.03, 2.98]