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. 2016 Apr 4;2016(4):CD011586. doi: 10.1002/14651858.CD011586.pub2

Barrois 1993.

Methods Multicentre parallel RCT (countries not reported)
Duration: 56 days
Unit of randomisation: participant
Unit of analysis: participant
Participants Inclusion criteria: people presenting with open necrotic pressure ulcers
Participants: 76 people with ulcers;
Ulcer size (cm²): 15 (reported comparable between groups)
Age, gender, ulcer location, ulcer stage not reported ("open necrotic pressure sore" interpreted by review authors as stage II or higher).
Interventions Intervention arm 1: gauze (Tulle) with povidone iodine
Intervention arm 2: hydrocolloid dressing (Granuflex)
Co‐interventions: cleansing with saline and debridement with forceps if necessary in both groups.
Outcomes Primary outcome: proportion of wounds completely healed
Primary outcome: adverse events
Secondary outcome: resource use (dressings per week)
Notes Reported in abstract only; authors not contacted due to date of publication
Funding: NR
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Reported in abstract only
Allocation concealment (selection bias) Unclear risk Reported in abstract only
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Reported in abstract only
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Quote: "Thirty‐eight patients received Granuflex and 38 received a Tulle dressing impregnated with povidone‐iodine antiseptic ointment......Two patients receiving Granuflex and five patients receiving the control dressing dropped out of the trial due to a deterioration in the pressure sore"
Comment: 7 of 72 patients were not included in the analyses; reasons specified.
Selective reporting (reporting bias) Unclear risk Reported in abstract only
Other bias Unclear risk Reported in abstract only