Analysis 14.11.

Comparison 14 Liraglutide 1.8 mg daily versus DPP‐4 inhibitors, Outcome 11 Beta‐cell function.

Beta‐cell function

Study	Description	Liraglutide 1.8 mg daily	Sitagliptin 100 mg daily	Difference between groups
L ‐ Pratley 2010	Fasting insulin (pmol/L)	1.29 (95% CI ‐8.04 to 10.62)	‐6.77 (95% CI ‐16.18 to 2.64)	8.06 (95% CI ‐4.51 to 20.63), P = 0.2083
L ‐ Pratley 2010		0.09 (95% CI 0.03 to 0.15)	‐0.04 (95% CI ‐0.10 to 0.02)	0.14 (95% CI 0.06 to 0.21), P = 0.0008
L ‐ Pratley 2010	Fasting insulin (pmol/L)	1.29 (95% CI ‐8.04 to 10.62)	‐6.77 (95% CI ‐16.18 to 2.64)	8.06 (95% CI ‐4.51 to 20.63), P = 0.2083
L ‐ Pratley 2010		0.09 (95% CI 0.03 to 0.15)	‐0.04 (95% CI ‐0.10 to 0.02)	0.14 (95% CI 0.06 to 0.21), P = 0.0008
L ‐ Pratley 2010		‐0.10 (95% CI ‐0.12 to ‐0.07)	‐0.03 (95% CI ‐0.06 to ‐0.00)	‐0.07 (95% CI ‐0.10 to ‐0.03), P = 0.0004