Comparison 7. Liraglutide 1.2 mg versus placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 HbA1c	3	1058	Mean Difference (IV, Random, 95% CI)	‐1.15 [‐1.33, ‐0.96]
2 HbA1c < 7%	3	1058	Risk Ratio (M‐H, Random, 95% CI)	2.91 [1.74, 4.87]
3 Hypoglycaemia	3	1058	Risk Ratio (M‐H, Random, 95% CI)	1.54 [0.54, 4.42]
4 Weight change	3	1058	Mean Difference (IV, Random, 95% CI)	‐0.75 [‐1.95, 0.45]
5 Adverse events			Other data	No numeric data
6 Systolic blood pressure	2	716	Mean Difference (IV, Random, 95% CI)	‐3.26 [‐7.71, 1.20]
7 Fasting plasma glucose (mmol/L)	3	1058	Mean Difference (IV, Random, 95% CI)	‐2.13 [‐2.59, ‐1.68]
8 Post‐prandial glucose (mmol/L)			Other data	No numeric data
9 Triglycerides (mmol/L)	1		Mean Difference (IV, Random, 95% CI)	Subtotals only
10 Total cholesterol (mmol/L)	1		Mean Difference (IV, Random, 95% CI)	Subtotals only
11 HDL‐cholesterol (mmol/L)	1		Mean Difference (IV, Random, 95% CI)	Subtotals only
12 LDL‐cholesterol (mmol/L)	1		Mean Difference (IV, Random, 95% CI)	Subtotals only
13 Beta‐cell function			Other data	No numeric data