Comparison 19. LY2189265 versus placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 HbA1c			Other data	No numeric data
2 HbA1c < 7%			Other data	No numeric data
3 Hypoglycaemia			Other data	No numeric data
3.1 LY 0.5/1.0 QW			Other data	No numeric data
4 Weight change (kg)	1		Mean Difference (IV, Random, 95% CI)	Subtotals only
4.1 LY 0.5/1.0 QW	1	130	Mean Difference (IV, Random, 95% CI)	‐1.32 [‐2.40, ‐0.24]
4.2 LY 1.0/1.0 QW	1	128	Mean Difference (IV, Random, 95% CI)	‐1.22 [‐2.30, ‐0.14]
4.3 LY 1.0/2.0 QW	1	128	Mean Difference (IV, Random, 95% CI)	‐2.43 [‐3.52, ‐1.34]
5 Adverse events			Other data	No numeric data
6 Systolic blood pressure (mm Hg)	1		Mean Difference (IV, Random, 95% CI)	Totals not selected
6.1 LY 0.5/1.0 QW	1		Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
6.2 LY 1.0/1.0 QW	1		Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
6.3 LY 1.0/2.0 QW	1		Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
7 Diastolic blood pressure (mm Hg)	1		Mean Difference (IV, Random, 95% CI)	Totals not selected
7.1 LY 0.5/1.0 QW	1		Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
7.2 LY 1.0/1.0 QW	1		Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
7.3 LY 1.0/2.0 QW	1		Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
8 Fasting plasma glucose (mmol/L)			Other data	No numeric data
9 Beta‐cell function			Other data	No numeric data