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. 2012 Aug 15;2012(8):CD008570. doi: 10.1002/14651858.CD008570.pub2

Summary of findings 2.

Comparing alternative mouse alone versus conventional mouse alone for preventing work‐related musculoskeletal disorders of the upper limb and neck in adults

Patient or population: patients with work‐related musculoskeletal disorders of the upper limb and neck in adults Settings: VDU users (> 20 hours per week) Intervention: alternative mouse alone (no arm support) Comparison: conventional mouse alone (no arm support)
Outcomes Illustrative comparative risks* (95% CI) Relative effect (95% CI) No of participants (studies) Quality of the evidence (GRADE) Comments
Assumed risk Corresponding risk
Conventional mouse alone Alternative mouse alone
Incidence of upper body disorder (neck, shoulder, and upper extremity) Questionnaire followed by medical examination Follow‐up: 12 months Study population RR 0.79 (0.52 to 1.21) 190 (2 studies) ⊕⊕⊕⊝ moderate1
333 per 1000 263 per 1000 (173 to 403)
Moderate
344 per 1000 272 per 1000 (179 to 416)
Incidence of neck/shoulder disorder Questionnaire followed by medical examination Follow‐up: 12 months Study population RR 0.62 (0.19 to 2) 182 (2 studies) ⊕⊕⊕⊝ moderate1
232 per 1000 144 per 1000 (44 to 463)
Moderate
250 per 1000 155 per 1000 (47 to 500)
Incidence of right upper extremity disorder Questionnaire followed by medical examination Follow‐up: 12 months Study population RR 0.91 (0.48 to 1.72) 182 (2 studies) ⊕⊕⊕⊝ moderate1
185 per 1000 168 per 1000 (89 to 318)
Moderate
184 per 1000 167 per 1000 (88 to 316)
Neck/shoulder discomfort score Questionnaire Follow‐up: 12 months The mean neck/shoulder discomfort score in the intervention groups was 0.04 standard deviations higher (0.26 lower to 0.33 higher) 195 (2 studies) ⊕⊕⊝⊝ low1,2 SMD 0.04 (‐0.26 to 0.33)
Right upper extremity discomfort score Questionnaire Follow‐up: 12 months The mean right upper extremity discomfort score in the intervention groups was 0 standard deviations higher (0.28 lower to 0.28 higher) 195 (2 studies) ⊕⊕⊝⊝ low1,2 SMD 0 (‐0.28 to 0.28)
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% CI) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: confidence interval; RR: risk ratio; VDU: visual display unit.
GRADE Working Group grades of evidence High quality: Further research is very unlikely to change our confidence in the estimate of effect. Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. Very low quality: We are very uncertain about the estimate.

1 Total number of participants < 300 (small sample size for categorical variable) 2 Measure of outcome based on subjective symptoms (detection bias)