Comparison 8. Budesonide versus placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Clinical response	4	161	Risk Ratio (M‐H, Random, 95% CI)	2.98 [1.14, 7.75]
2 Clinical response sensitivity analysis excluding Miehlke 2014	3	94	Risk Ratio (M‐H, Fixed, 95% CI)	4.56 [2.43, 8.55]
3 Histological response	4	161	Risk Ratio (M‐H, Random, 95% CI)	2.68 [1.37, 5.24]
4 Histological response sensitivity analysis excluding Miehlke 2014	3	94	Risk Ratio (M‐H, Fixed, 95% CI)	4.15 [2.25, 7.66]
5 Maintenance of clinical response	3	172	Risk Ratio (M‐H, Fixed, 95% CI)	3.30 [2.13, 5.09]
6 Maintenance of histological response	2	80	Risk Ratio (M‐H, Fixed, 95% CI)	3.17 [1.44, 6.95]
7 Adverse events	5	290	Risk Ratio (M‐H, Fixed, 95% CI)	1.18 [0.92, 1.51]
8 Withdrawals due to adverse events	5	290	Risk Ratio (M‐H, Fixed, 95% CI)	0.97 [0.43, 2.17]
9 Serious adverse events	4	175	Risk Ratio (M‐H, Fixed, 95% CI)	1.11 [0.15, 8.01]