Table 5.
Overview of Test Guidelines and other documents for mammalian toxicology already updated or currently under discussion in the OECD TGP and WPMN.
| Test Guideline Title | Lead Country |
|---|---|
| Published | |
| TG412 Subacute Inhalation Toxicity: 28-Day Study (OECD, 2018a) | |
| TG413 Subacute Inhalation Toxicity: 90-day Study (OECD, 2018b) | |
| SPSF submitted in Nov. 2018 | |
| Applicability of the key event based Test Guideline 442D for in vitro skin sensitisation testing of nanomaterials | Switzerland |
| Documents being drafted by the WPMN | |
| New TG on toxicokinetics or Amendments to TG417 'Toxicokinetics' to accommodate nanomaterials | The Netherlands |
| Guidance documents and other documents | |
| Published | |
| Update of GD 39 (OECD, 2018a, OECD, 2018b, OECD, 2018c, OECD, 2018d, OECD, 2018e) | |
| Documents on-going in the TGP | |
| Guidance Document on the Adaptation of In Vitro Mammalian Cell Based Genotoxicity TGs for Testing of Manufactured Nanomaterials | EC-JRC |