Table 5.
Cox Proportional Hazard Models Clinical and Procedural Predictors of Target Vessel Failure and MACE at 1-year.
Predictors of Target Vessel Failure* | Univariate | Multivariable | ||||
---|---|---|---|---|---|---|
HR | 95% CI | P Value | HR | 95% CI | P value | |
Subintimal Tracking | 2.74 | 1.00–7.54 | 0.04 | 1.51 | 0.38–6.00 | 0.55 |
Japanese CTO Score‡ | 1.75 | 1.20 −2.56 | 0.004 | 1.40 | 0.74–2.62 | 0.30 |
History of Coronary Artery Bypass Grafting | 1.51 | 0.63–3.66 | 0.85 | 0.75 | 0.20–2.77 | 0.66 |
History of Percutaneous Coronary Intervention | 2.51 | 0.74–8.56 | 0.14 | 4.87 | 0.81–29.21 | 0.08 |
Retrograde approach | 2.38 | 0.99–5.7 | 0.053 | 1.55 | 0.39–6.1 | 0.53 |
IVUS Vascular injury | 3.83 | 0.88–16.50 | 0.07 | 2.50 | 0.25–24.86 | 0.43 |
Minimal Stent Area | 0.87 | 0.63–1.19 | 0.37 | 0.98 | 0.68–1.41 | 0.92 |
Angiographic and IVUS predictors of MACE* | HR | 95% CI | P Value | HR | 95% CI | Adjusted P value |
Subintimal Tracking | 2.24 | 0.93–5.41 | 0.06 | 1.83 | 0.52–6.46 | 0.34 |
Japanese CTO Score‡ | 1.60 | 1.13–2.26 | 0.008 | 1.37 | 0.80–2.36 | 0.25 |
History of Coronary Artery Bypass Grafting | 1.60 | 0.70–3.50 | 0.27 | 0.83 | 0.26–2.62 | 0.74 |
History of Percutaneous Coronary Intervention | 1.69 | 0.63–4.51 | 0.30 | 2.14 | 0.57–8.04 | 0.26 |
Retrograde approach | 2.04 | 0.91–4.55 | 0.08 | 1.30 | 0.38–4.27 | 0.78 |
IVUS Vascular injury | 2.14 | 0.73–6.27 | 0.16 | 1.02 | 0.22–4.76 | 0.97 |
Minimal Stent Area | 0.99 | 0.76–1.28 | 0.01 | 1.12 | 0.84–1.49 | 0.46 |
Multivariable Models also adjusted for Age, Gender, DM, and Ejection Fraction
Log rank test used
treated as an ordinal variable
Abbreviations: CTO – chronic total occlusion, IVUS – intravascular ultrasound.