Figure 6.

Representative H&E images (A-B) of the metastatic sarcoma-not otherwise specified to the lung with unknown primary site. The tumor shows a mixture of spindled to epithelioid cells in a whorling and nodular growth pattern. (C) Schematic diagrams of the novel fusion MYLK-BRAF joining MYLK exon24 to BRAF exon10. The BRAF protein kinase domain is included in the predicted fusion protein. (Magnification: A: 200x, B: 400x) Protein domain info taken from http://www.uniprot.org/

Igl: immunoglobulin-like domain

FN3: Fibronectin type-III domain