Table 1.
Quantification of Content Present within Myocytes from Differing Disease Etiologies, Presented as Percentage of Cell Area
| Case (n Cells) | TT (%) | LT (%) | TA (%) | TT ± 5° Minor Axis (%) |
|---|---|---|---|---|
| Sham (5) | 78 ± 11 | 4 ± 2 | 9 ± 5 | 57 ± 12 |
| AB (3) | 19 ± 14a | 5 ± 1 | 37 ± 13 | 36 ± 9a |
| MIDistal (3) | 56 ± 15 | 7 ± 1 | 11 ± 6 | 48 ± 6 |
| MIIntermediate (3) | 57 ± 4a | 10 ± 2a | 10 ± 7 | 37 ± 4a |
| MIProximal (3) | 55 ± 16 | 12 ± 3a | 12 ± 6 | 34 ± 4a |
| Distal tissue (1000) | 18.9 ± 1.0 | – | 9.5 ± 2.0 | – |
| Proximal tissue (1000) | 10.1 ± 0.8b | – | 16.0 ± 2.0 | – |
Refer to the Supporting Material for full range of cardiomyocytes considered herein. Data presented as mean SD. TT denotes a “hit” from the transverse tubule filter. Similarly, LT and TA denote “hits” from the longitudinal and tubule absence filters, respectively. Distal and Proximal tissue results were analyzed using the bootstrapping method explained in Supporting Materials and Methods, Section S3.4; n denotes number of synthetic images created for analysis.
a
p < 0.05 compared to sham result.
b
p < 0.05 compared to distal result.