Table 2.
VEO-IBD [n = 57] | Older onset IBD [n = 58] | |
---|---|---|
Male, n [%] | 40 [70] | 40 [69] |
Age at diagnosis, median, yr [IQR] | 2.2 [1.3, 3.4] | 13.0 [9.5, 13.6] |
A1a 0–<10 yr, n | 57 | 5 |
A1b 10–<17 yr, n | 0 | 53 |
IBD subtype, n [%] | ||
Crohn’s disease | 39 [68] | 44 [76] |
IBD-unclassified | 16 [28] | 5 [9] |
Ulcerative colitis | 2 [4] | 9 [15] |
Ulcerative colitis/IBD-U extent of disease | ||
E1: Ulcerative proctitis | 0 [0] | 1 [7] |
E2: Left-sided colitis | 6 [33] | 0 |
E3: Extensive | 3 [17] | 1 [7] |
E4: Pancolitis | 9 [50] | 12 [86] |
Crohn’s disease characteristics | ||
Lower GI involvement, n [%] | ||
L1: Distal 1/3 Ileum/limited caecal disease | 0 [0] | 4 [9] |
L2: Colonic only | 24 [49] | 8 [18] |
L3: Ileocolonic | 7 [44] | 19 [43] |
None | 3 [8] | 0 [0] |
Upper GI involvement, n [%] | ||
L4a: Upper disease proximal to ligament of Treitz [LOT] | 19 [49] | 11 [25] |
L4b: Upper disease distal to LOT and proximal to distal 1/3 ileum | 5 [13] | 19 [43] |
Behaviour phenotype, n [%] | ||
B1: Non-stricturing, non-penetrating | 31 [80] | 31[70] |
B2: Stricturing | 4 [10] | 7 [16] |
B3: Penetrating | 4 [10] | 4 [9] |
B4: Both Stricturing and penetrating | 0 [0] | 2 [5] |
Perianal involvement, n [%] | 14 [36] | 5 [11] |
VEO-IBD, very early onset inflammatory bowel disease; yr, years; IQR, interquartile range.