Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Feb 26;47(8):4198–4210. doi: 10.1093/nar/gkz106

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

PMC Copyright notice

Figure 6. — Association between geometric and sequence conservations of ribosomal rRNA. (A) A map of the secondary structure of the 23S rRNA in E. coli, colored by the distance from tunnel (see also Supplementary Figure S5). (B) For a given species and distance d, we look at all the rRNA nucleotides located within distance d from the tunnel, and we compute the frequency of conserved elements (24). We plot this frequency as a function of d for all the species of our dataset (see also Supplementary Figure S6). (C) We study the local conservation of rRNA nucleotides along the tunnel: Upon dividing the tunnel into regions of 15 Å along the centerline, we consider for each region all the rRNA nucleotides that are the closest and located within 25 Å, and we compute the associated number of conserved, domain-specific and universally conserved elements. We show here the resulting plots for E. coli (up) and H. sapiens (down) (for other species, see Supplementary Figure S6).