FIG. 2.

LPS failed to improve the cardioprotection of MyD88^−/− MSCs. MyD88^−/− MSC, with or without LPS pretreatment, were infused into the coronary circulation. (A, B) Representative LVP recording traces from hearts infused with MyD88^−/− MSCs and MyD88^−/− MSCs + LPS as a function of time (n = 5). The LVDP in MyD88^−/− group (square) and MyD88^−/− MSCs + LPS group (circle, n = 5) is presented. The line graphs represent changes in LVDP (% of equilibrium, C), +dP/dt (% of equilibrium, D), −dP/dt (% of equilibrium, E), and EDP (F) over time. Results are reported as the mean ± SEM. Arrows represent the starting time points of ischemia.