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. 2019 Apr 24;7:e6822. doi: 10.7717/peerj.6822

Table 1. Distribution of the DEGs of Burkholderia zhejiangensis CEIB S4-3 at 3 and 9 h in KEGG.

Metabolic pathway 3 h 9 h
MP* WMP MP* WMP
Biosynthesis of antibiotics 52 9 111 51
Biosynthesis of secondary metabolites 48 20 113 57
Quorum sensing 37 49 139 99
Oxidative phosphorylation 24 5 38 15
Biosynthesis of amino acids 22 10 47 19
Two-component system 21 12 41 51
Biosynthesis of unsaturated fatty acids 19 19 19
Biotin metabolism 19 19 19
Fatty acid biosynthesis 19 19 19
Fatty acid metabolism 19 39 19
Phenylalanine metabolism 19 14 37
Carbon metabolism 17 6 65 25
Chloroalkane and chloroalkene degradation 17 20 1
ABC transporters 16 37 118 106
Glycine, serine, and threonine metabolism 16 2 25 18
Ribosome 15 2 38
2-Oxocarboxylic acid metabolism 14 24
Degradation of aromatic compounds 14 6 17 5
Arginine and proline metabolism 13 13
C5 Branched dibasic acid metabolism 13 15
Glycolysis/gluconeogenesis 13 22 10
Purine metabolism 13 4 18 12
Valine, leucine, and isoleucine biosynthesis 13 16 4
Valine, leucine, and isoleucine degradation 13 33 5
Butanoate metabolism 12 43
Pyruvate metabolism 12 29 5
Ascorbate and aldarate metabolism 11 11 3
Chlorocyclohexane and chlorobenzene degradation 10 10 4
Flagellar assembly 10 2 10 1
Tryptophan metabolism 10 4 31 5
Beta Alanine metabolism 9 3 19
Fatty acid degradation 9 5 32 1
Glycerolipid metabolism 9 14
Histidine metabolism 9 9 4
Limonene and pinene degradation 9 15
Lysine degradation 9 31
Pyrimidine metabolism 9 4 15 2
Citrate cycle (TCA cycle) 7 22 5
Glyoxylate and dicarboxylate metabolism 7 7 35 12
Methane metabolism 7 16 6
Benzoate degradation 6 28 5
Cysteine and methionine metabolism 6 4 7 7
Phosphonate and phosphinate metabolism 6 6
Synthesis and degradation of ketone bodies 6 15
Galactose metabolism 5 4 4
Nitrogen metabolism 5 11 9 12
One carbon pool by folate 5 7
Dioxin degradation 4 4
Fluorobenzoate degradation 4 4 5
Folate biosynthesis 4 4 4
Naphthalene degradation 4 7 1
Polycyclic aromatic hydrocarbon degradation 4 4 3
Toluene degradation 4 1 4 5
Beta-Lactam resistance 3 10
Cyanoamino acid metabolism 3 3
Novobiocin biosynthesis 3 3
Phenylalanine, tyrosine, and tryptophan biosynthesis 3 3 15 4
Propanoate metabolism 3 27 6
Taurine and hypotaurine metabolism 3 4
Tyrosine metabolism 3 1 13 1
Alanine, aspartate, and glutamate metabolism 2 5 12 3
Bacterial chemotaxis 2 17 9
Carbon fixation in photosynthetic organisms 2 5 2
Pentose phosphate pathway 2 2 4
Polyketide sugar unit biosynthesis 2 2
RNA degradation 2 2 4 6
Streptomycin biosynthesis 2 2
Ubiquinone and other terpenoid quinone biosynthesis 2 5 2
Aminobenzoate degradation 1 5 7 6
Arginine biosynthesis 1 3 3 3
Fructose and mannose metabolism 1 1 2 4
Lysine biosynthesis 1 1
Porphyrin and chlorophyll metabolism 1 5 4
Riboflavin metabolism 1 3
RNA polymerase 1 3
Pantothenate and CoA biosynthesis 11 4 8
Nicotinate and nicotinamide metabolism 5 8 2
Starch and sucrose metabolism 5 8
Sulfur metabolism 5 7 9
Non homologous end joining 3 3
Amino sugar and nucleotide sugar metabolism 2 2
Glycerophospholipid metabolism 1 3 2
Styrene degradation 1 3 1
Pentose and glucuronate interconversions 1 5 1
Xylene degradation 1 1
Base excision repair 1
Nucleotide excision repair 1
D-Glutamine and D-glutamate metabolism 1
Aminoacyl tRNA biosynthesis 1
alpha-Linolenic acid metabolism 1
Thiamine metabolism 2
Monobactam biosynthesis 2
DNA replication 3 2
Inositol phosphate metabolism 3
Bacterial secretion system 3 4
Selenocompound metabolism 3 4
Mismatch repair 3 1
Protein export 4 1
Homologous recombination 4
Caprolactam degradation 7
Geraniol degradation 7
Cationic antimicrobial peptide (CAMP) resistance 8
Terpenoid backbone biosynthesis 9 1
Glutathione metabolism 14 13

Note:

The numbers represent the genes of the metabolic pathway in each condition.

*

MP, methyl parathion to 0.2 mM.

WMP, without methyl parathion.