Table 2.
Examples of Studies Reporting Adult Height in Girls Treated With a GnRHa for CPP
First Author | Year of Publication | No. of Girls Participating | Modality Used and Duration of GnRH Treatmenta | Adult Height Achieved, Mean ± SD (cm) | Height Increase Above Predicted at Baseline (cm) |
---|---|---|---|---|---|
Heger [24] | 1999 | 50 | Depot triptorelin 4.4 ± 2.1 y | 160.6 ± 8.0 | 5.7 |
Antoniazzi [25] | 2000 | 71 | Depot triptorelin, buserelin nasal spray 16–56 mo | 154.4 ± 5.6 | 2-7 |
Lazar [32] | 2007 | 115 | Depot decapeptyl 2.8–4.8 y | 160.35 ± 5.05 | 5 |
Pasquino [26] | 2008 | 87 | Depot triptorelin 4.2 ± 1.6 y | 159.8 ± 5.3 | 5.1 |
Nabhan [27] | 2009 | 26 | Depot leuprolide 3.6 ± 2.1 y | 163 ± 7.6 | 4.5 |
Magiakou [22] | 2010 | 33 | Depot triptorelin 2.75 y | 158.5 | 6.95 |
Poomthavorn [21] | 2011 | 47 | Depot leuprolide or triptorelin 3.4 ± 1.5 y | 158.6 ± 5.2 | 4.7 |
Bertelloni [11] | 2015 | 25 | Depot triptorelin, 3.05 ± 0.9 y | 158.25 ± 5.8 | 3 |
Lee [28] | 2018 | 84 | Depot leuprolide 2.98 ± 0.73 y | 160.1 ± 5 | 4 |
Duration data reported as mean ± SD or as a range.