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. Author manuscript; available in PMC: 2019 May 28.
Published in final edited form as: Biochem Biophys Res Commun. 2019 Apr 8;513(2):486–493. doi: 10.1016/j.bbrc.2019.03.199

Fig. 3. CD38 is induced in non-senescent cells by secreted factors (SASP) from senescent cells.

Fig. 3.

(A) Scheme showing production of control conditioned media (CM) and SASP (senescent cell conditioned media) from HUVECs or PDPs for treatment of non-senescent cells. (B) Relative CD38 mRNA expression and activity in BMDMs treated with CM or SASP from x-ray- (n=7–9) or γ-IR-treated (n=3) HUVECs. (C and D) CD38 mRNA expression and activity in BMDMs treated with CM or SASP from PDP originating from (patient 1 in C) or (patient 2 in D) (n=2–3). (E) Relative CD38 expression (n=4–6) in HUVECs treated with CM or SASP from γ-IR MEFs. Data are mean ± SE, *p < 0.05 vs control.