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. Author manuscript; available in PMC: 2019 May 28.
Published in final edited form as: Biochem Biophys Res Commun. 2019 Apr 8;513(2):486–493. doi: 10.1016/j.bbrc.2019.03.199

Fig. 4. CD38 and other M1 markers in macrophages treated with SASP.

Fig. 4.

(A) Representative immunoblots demonstrating levels of CD38 in BMDMs treated with CM (control conditional media) or SASP (x-ray- or γ-IR-induced senescent cell conditioned media) from PDPs or HUVECs. (B) mRNA expression of other M1 markers, namely IL-6, IL-8, and Nos2 (inducible nitric oxide synthase), in BMDMs treated with CM or SASP from PDPs. (C) Model of SASP-induced CD38 expression in macrophages. Data are mean ± SE, *p < 0.05 vs control.