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Markers and mediators of systemic injury in acute pancreatit
| Markers and mediators of systemic injury |
| Released from acinar cells |
| Trypsin |
| Inflammatory cells and their products |
| Neutrophils |
| NET |
| Inflammasome |
| Cytokines |
| IL-6 |
| IL-1β |
| TNF-α |
| IL-12 |
| IL-18 |
| Adipokines |
| Resistin |
| Visfatin |
| Lipid mediators: |
| Unsaturated fatty acids |
| Platelet activating factor |
| DAMPs |
| HMGB1 |
| sRAGE |
| ds-DNA |
| Histones/ nucleosomes |
| S100 proteins |
| ATP |
| Extracellular matric (e.g. hyaluronan) |
