Each bar represents the proportion of infants whose caregiver reported use of a medication in that class during the prior three-month period at the corrected age in months as noted. The proportion of those who were on at least one respiratory drug increased significantly over time, as did the use of inhaled steroids and inhaled bronchodilators. Conversely, diuretic use decreased significantly over the first year of life. (*P≤0.0005 by chi-square.) The denominators (n) for each time period are 712 (month 3), 708 (month 6), 688 (month 9), and 696 (month 12).