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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Neurobiol Aging. 2019 Jan 21;77:26–36. doi: 10.1016/j.neurobiolaging.2019.01.008

Table 3:

Proportion of individuals having each combination of either two or three pathologies in the entire cohort of 161 CN subjects

Pathology 1 Pathology 2 Pathology 3

Tau α-Synuclein TDP-43 Vascular
Combinations of any two pathologies

β-Amyloid 40% 12% 14% 28% NA
Tau 11% 11% 20% NA
α-Synuclein 3% 5% NA
TDP-43 8% NA

Combinations of any three pathologies

β-Amyloid 10% NA α-Synuclein
β-Amyloid 8% 2% NA TDP-43
β-Amyloid 16% 4% 6% NA Vascular
Tau 2% NA TDP-43
Tau 3% 4% NA Vascular
α-Synuclein 1% NA Vascular