Table 5:

Trend test of number of pathologies

	Trend test
	Est. (95% CI)	p-values
Clinical scores
MMSE / 30	−0.12 (−0.34, −0.01)	0.29
WMS Logical Memory Delayed Recall / 50	−0.30 (−1.4, −0.10)	0.53
Boston Naming / 60	−0.10 (−0.89, −0.15)	0.81
Controlled Oral Word Association	0.65 (−2.4, 0.72)	0.67
WAIS-Block Design / 51	0.22 (−1.0, −0.23)	0.73
AVLT Delayed Recall / 15	−0.62 (−1.1, −0.04)	0.01
Trails A / 180	−0.30 (−4.2, 2.1)	0.88
Trails B / 300	0.38 (−8.9, 5.2)	0.94
Total UPDRS / 44	0.24 (−0.29, 0.17)	0.37
BDI-II / 63	0.60 (−0.18, 0.20)	0.13
Gray matter volumes (cm3)
Amygdala	−0.007 (−0.04, 0.03)	0.68
Hippocampus	0.03 (−0.06, 0.10)	0.50
Entorhinal cortex	0.04 (−0.03, 0.10)	0.26
Lateral frontal	−0.60 (−2.0, 0.90)	0.43
Lateral parietal	−0.40 (−1.0, 0.40)	0.32
Lateral temporal	−0.40 (−1.0, 0.70)	0.47
Medial frontal	−0.20 (−0.90, 0.50)	0.55
Medial parietal	−0.20 (−0.70, 0.20)	0.29

APOE= apolipoprotein ; AVLT = auditory verbal learning test; BDI = Becks depression inventory; UPDRS = Unified Parkinson’s disease rating scale (modified version used) ; WAIS = Wechsler Adult Intelligent scale