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. Author manuscript; available in PMC: 2019 Nov 9.
Published in final edited form as: J Neurosurg. 2018 Oct 19;131(2):517–525. doi: 10.3171/2018.4.JNS18211

TABLE 3.

Literature review of SCO cases

Authors & Year Age (yrs), Sex Presenting Sx Primary or Progression/Recurrence Size (cm) Tx Outcome/Subsequent Tx
Roncaroli et al., 2002 53–71 (mean 61.6); 2F, 3M PHP Primary NA TSR FU 2–68 mos (mean 35.4 mos); no recurrences noted
PHP Primary NA TSR
PHP Primary NA TSR
PHP, VD Primary NA TSR
PHP, VD Primary NA Craniotomy
Kloub et al., 2005 71, F VD, PHP (mild) P/R: primary TSR 11 yrs prior; 1st sign of recurrence 8 yrs prior NA TSR Add’l resection for residual tumor 1 yr postop
76, M Epistaxis P/R: primary TSR 10 yrs prior w/ add’l resection & radiation 7 yrs prior NA TSR NA
Dahiya et al., 2005 26, M HA, VD, N/V, impotence Primary 1.5–2 (diam) TSR, craniotomy, proton beam radiation Stable (7 yrs)
55, F HA, VD Primary 6.5 × 3.3 × 4.0 TSR Stable (6 mos)
Vajtai et al., 2006 48, F Fatigue, VD Primary 1.8 × 1.5 × 1.3 TSR Stable (16 yrs)
Coiré et al., 2009 NA NA Primary NA TSR Add’l TSR & radiation 5 mos postop
Borota et al., 2009 NA NA NA NA TSR, RT Regrowth over 30-mo FU period
Matyja et al., 2010 63, F PHP, N/V, HA, VD Primary 2.1 × 1.8 × 1.9 TSR Stable (28 mos)
65, F PHP P/R: primary TSR 3 yrs prior 1.8 × 1.9 × 2.1 Frontal craniotomy Stable (20 mos)
Demssie et al., 2011 59, M PHP, VD, N/V Primary NA TSR, RT 2 add’l TSR 9 mos postop
Vajtai et al., 2011 55, F PHP Primary 2.7 × 2.6 × 2.5 TSR
Mlika et al., 2011 45, F VD, HA Primary 2.0 × 1.5 × 1.0 TSR Stable (3 mos)
Romero-Rojas et al., 2011 42, F Oligomenorrhea Primary 3.2 × 3.2 × 3.4 “Resection” NA
Borges et al., 2011 70, F VD Primary 3.3 × 2.4 × 3.0 TSR Recurrence & add’l TSR 13 yrs postop
Ogiwara et al., 2011 39, M HA, memory loss P/R: primary craniotomy & radiation 13 mos prior; add’l resection 4 mos prior w/ residual 2.7 × 2.4 × 2.8 TSR Stable residual (1 yr)
Singh et al., 2012 68, M VD, HA Primary 3.1 × 2.9 × 3.0 TSR Died from unrelated causes 1 mo postop
Alexandrescu et al., 2012 24, F HA, amenorrhea, VD Primary 2.5 × 1.8 TSR Stable (6 mos)
Fujisawa et al., 2012 68, M PHP, VD Primary NA TSR Transcranial re-resection for residual tumor & radiation 18 mos postop
Rotman et al., 2014 88, M PHP, VD, fatigue Primary 2.7 × 2.0 × 1.7 TSR NA
Mu et al., 2015 35, F Amenorrhea, lactation, VD Primary 2.5 × 3.0 × 1.0 Craniotomy Stable (21 mos)
62, F Incidental finding Primary 2.3 × 1.7 × 2.0 Craniotomy Stable (15 mos)
Zygourakis et al., 2015 31, F VD, HA Primary 2.2 (diam) TSR Stable (6 mos)
53, F HA Primary 0.7 (diam) Biopsy Stable (2 mos)
Custodio et al., 2016 60, M N/V, syncope, PHP, hyponatremia Primary 3.1 × 2.3 × 2.0 TSR Stable (18 mos)
Hasiloglu et al., 2016 40, M PHP Primary 2.1 × 1.9 × 3.6 TSR Add’l TSR 1 yr postop for residual tumor
60, M HA, VD Primary 3.1 × 2.0 × 2.3 TSR Stable (12 mos)
55, M HA, VD Primary 2.0 × 1.9 × 1.8 TSR Stable (6 mos)
Vuong et al., 2016 70, M HA, VD Primary 6.0 × 5.5 × 4.5 TSR Stable (6 mos)
Guadagno et al., 2016 77, M HA, VD Primary TSR Stable (14 mos)
Billeci et al., 2017 61, M HA Primary 2.2 × 1.8 × 2.7 TSR Add’l TSR for residual tumor 16 mos postop; stable (14 mos)
65, F HA, VD Primary 2.0 × 1.5 × 1.0 TSR Stable (28 mos)
Osman & Wild, 2017 56, M HA, altered LOC, VD Primary 2.5 × 4.4 × 2.5 Craniotomy (urgent), EVD Stable (6 mos)
Manoranjan et al., 2017 60, M VD P/R: primary resection 13 yrs prior; biopsy & RT for residual tumor 11 yrs prior 2.6 × 3.0 × 2.4 TSR Stable (9 mos)
Sali et al., 2017 64, M VD P/R: primary TSR 4 yrs prior 2.2 × 2.1 × 2.5 TSR NA

Add’l = additional; diam = diameter; EVD = external ventricular drain; FU = follow-up; LOC = level of consciousness; N/V = nausea/vomiting; PHP = panhypopituitarism; P/R = progression/recurrence; RT = radiotherapy; TSR = transsphenoidal resection; VD = visual deficit.

The 6 cases reported in the current study (including the 3 previously reported by Miller et al.23) are not included in this table. For a summary of those cases, please see Table 1.