Table 4.

Association between cognition and v_L and K_i, for NAWM, WMH and CGM, in healthy controls, uncorrected

	Overall		Executive		Speed		Memory
	β	p-value	β	p-value	β	p-value	β	p-value
v L
NAWM	0.000	1	0.096	0.56	0.021	0.90	-0.108	0.51
WMH	-0.094	0.57	0.020	0.91	-0.065	0.69	-0.192	0.24
CGM	-0.166	0.31	-0.67	0.68	-0.136	0.41	-0.226	0.17
K i
NAWM	-0.237	0.15	-0.326	0.04*	-0.339	0.04*	0.029	0.86
WMH	-0.304	0.06	-0.366	0.02	-0.340	0.03	-0.105	0.52
CGM	0.204	0.21	0.051	0.31	0.143	0.39	0.333	0.04

Overall overall cognitive function, Executive executive function, Speed information processing speed, vL leakage volume, Ki leakage rate, NAWM normal appearing white matter, WMH white matter hyperintensities, CGM cortical grey matter.

βvalues represent standardized regression coefficients.

* p < 0.05 after correcting for age, sex, educational level and Hamilton Anxiety and Depression Score.