Table 3.
The genotype and allele frequencies of promoter polymorphisms in IL-6 gene in CAD patients and healthy control subjects
IL-6 SNP | Genotype and allele | Cases (n = 265) | Controls (n = 205) | OR | 95% CI | P value |
---|---|---|---|---|---|---|
rs1800795 (G/C) | GG | 163 (61.50%) | 145 (70.73%) | 1.58 | 1.024–2.23 | 0.04* |
GC | 99 (37.35%) | 57 (27.80%) | ||||
CC | 03 (1.13%) | 03 (1.46%) | ||||
G | 425 (80.18%) | 347 (84.63%) | 1.36 | 0.96–1.91 | 0.08 | |
C | 105 (19.81%) | 63 (15.36%) |
*P value < 0.05 is considered as significant