Table 2.
Influence of β-globin gene haplotypes on malondialdehyde (MDA), C-reactive protein, total antioxidant power (FARP) and total thiol levels among SCA patients
| Haplotypes with genotype frequency | CRP | MDA | FARP | THIOL | HbF |
|---|---|---|---|---|---|
| Arab-Indian haplotype (n = 65) | 4.35 ± 4.30 | 3.46 ± 2.43 | 435.22 ± 92.11 | 229.15 ± 41.44 | 22.71 ± 5.23 |
| Atypical Arab-Indian (n = 11) | 4.47 ± 4.08 | 3.80 ± 1.14 | 392.55 ± 68.11 | 225.0 ± 30.50 | 20.85 ± 3.02 |
| Atypical Benin (n = 3) | 15.76 ± 2.55 | 5.56 ± 0.57 | 254.0 ± 3.46 | 156.67 ± 11.37 | 9.73 ± 0.59 |
| Atypical Bantu (n = 3) | 21.93 ± 1.74 | 7.13 ± 0.32 | 245.33 ± 13.61 | 101.0 ± 3.60 | 3.83 ± 0.46 |
| Atypical Cameroon (n = 5) | 13.32 ± 3.79 | 4.92 ± 0.45 | 305.60 ± 15.70 | 148.80 ± 19.67 | 12.84 ± 0.67 |
| Benin haplotype (n = 3) | 19.0 ± 0.14 | 6.76 ± 0.15 | 245.67 ± 14.0 | 135.0 ± 9.53 | 7.0 ± 0.21 |
| Atypical Cameroon/Benin (n = 4) | 18.20 ± 0.85 | 6.37 ± 0.55 | 273.50 ± 11.12 | 148.50 ± 12.87 | 9.17 ± 0.38 |
| Cameroon haplotype (n = 1) | 17.91 | 4.60 | 266.0 | 169.0 | 10.1 |
| Rare 1 (n = 3) | 6.64 ± 6.38 | 4.70 ± 0.26 | 303.67 ± 33.17 | 148.0 ± 13.85 | 13.7 ± 1.48 |
| Rare 2 (n = 2) | 10.08 ± 9.88 | 4.35 ± 0.35 | 365.0 ± 49.49 | 195.0 ± 60.81 | 14.7 ± 0.1 |
Values are expressed in mean with standard deviation (Mean ± SD)
n Number of subjects