Fig. 2.

Association between neutrophilic uPAR expression and circulating suPAR in critically ill patients. Flow-cytometric expression of uPAR (CD87) on circulating neutrophils and serum levels of suPAR were analyzed in 27 healthy volunteers, 48 standard care patients with bacterial infections, and 87 intensive care patients at baseline. a Correlation analysis of uPAR expressed on neutrophils and suPAR in peripheral blood in the different cohorts. Correlation coefficient (r) and p values are based on Spearman rank correlation test and given in the figure. b uPAR expression by neutrophils and suPAR serum concentrations in septic and non-septic ICU patients. c uPAR expression by neutrophils and suPAR serum concentrations in ICU patients, dependent on the stage of acute kidney injury (AKI) as defined by the Acute Kidney Injury Network (AKIN). Significant differences are indicated by *p < 0.05, **p < 0.01, and ***p < 0.001