Fig. 3.

Prognostic relevance of neutrophilic uPAR expression and circulating suPAR levels. Flow-cytometric expression of uPAR (CD87) on circulating neutrophils and serum levels of suPAR were measured at admission to the ICU and 48 h later (day 3). a Neutrophilic uPAR expression and circulating suPAR levels in ICU patients, divided into patients that survived and patients that died at the ICU. b Kaplan-Meier survival curves display the different survival rates of ICU patients, depending on either high or low neutrophilic uPAR (cut-off 75%) or circulating suPAR levels (cut-off 11.95 ng/ml) at ICU admission. c ROC curve analyses comparing the predictive power of suPAR (AUC 0.727) and uPAR (AUC 0.665) at admission for mortality with the established clinical ICU score APACHE II (AUC 0.781). Abbreviations: APACHE Acute Physiology and Chronic Health Evaluation, AUC area under the curve, ROC receiver operating characteristics