Table 3.
Correlation analysis between serum suPAR and neutrophilic uPAR with other laboratory and clinical parameters markers in ICU patients
| Parameter | suPAR (serum) | uPAR (neutrophils) | ||
|---|---|---|---|---|
| r | p | r | p | |
| Inflammation | ||||
| C-reactive protein | 0.232 | 0.015 | − 0.264 | 0.007 |
| Procalcitonin | 0.422 | < 0.001 | − 0.329 | 0.001 |
| WBC | 0.169 | 0.059 | − 0.227 | 0.017 |
| Interleukin-6 | 0.506 | < 0.001 | − 0.345 | 0.001 |
| TNF | 0.253 | 0.009 | − 0.24 | 0.013 |
| Interleukin-10 | 0.248 | 0.012 | − 0.24 | 0.014 |
| Renal function | ||||
| Creatinine | 0.512 | < 0.001 | − 0.342 | 0.001 |
| GFR (creatinine) | − 0.511 | < 0.001 | 0.289 | 0.003 |
| Urea | 0.469 | < 0.001 | − 0.271 | 0.006 |
| Liver function | ||||
| AST | 0.3 | 0.003 | − 0.214 | 0.028 |
| ALT | 0.159 | 0.075 | − 0.121 | 0.137 |
| Bilirubin | 0.5 | < 0.001 | − 0.238 | 0.014 |
| Albumin | − 0.24 | 0.019 | 0.204 | 0.04 |
| Gamma GT | 0.227 | 0.02 | − 0.19 | 0.043 |
| Alkaline phosphatase | 0.246 | 0.018 | − 0.231 | 0.025 |
| Clinical course | ||||
| Days in hospital | 0.301 | 0.009 | − 0.093 | 0.238 |
| Days at ICU | 0.21 | 0.027 | − 0.03 | 0.391 |
Abbreviations: ALT/AST alanine/aspartate aminotransferase, GFR glomerular filtration rate, ICU intensive care unit, TNF tumor necrosis factor, (s)uPAR (soluble) urokinase plasminogen activation receptor, WBC white blood cell count
Spearman rank correlation test, significant correlations (p < 0.05) highlighted in italics