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Whole mount imaging of vascularization in allogeneic islet grafts transplanted in NOD recipients. (A) Lectin (magenta) perfused grafts illustrate vascularization of unencapsulated or encapsulated islet (GFP, green) grafts. (B) Quantification of vascularization area within image field of view demonstrates significantly higher vascularization in PEG-RGD grafts compared to alginate. Scale bars = 200 μm. * P < 0.05 by Student’s t-test.
