Table 3.
Association of haplotypes in the CDKAL1 gene with gestational diabetes mellitus.
SNP combinations | Frequency (%) | ORa | 95% CI | P b |
---|---|---|---|---|
Block 4 | ||||
rs4712527 rs9356744 rs9368222 rs7748720 rs9295478 rs6935599 rs7747752 rs6928012 | ||||
AGAAAGGG | 39.88 | 1 | ||
AACAGACA | 31.24 | 0.82 | 0.62-1.07 | 0.145 |
GACGGACG | 14.08 | 0.52 | 0.37-0.74 | 0.0003 |
AACAAGGG | 6.72 | 0.98 | 0.62-1.55 | 0.931 |
Rare (<0.05) | 8.08 | 0.86 | 0.56-1.33 | 0.505 |
| ||||
Block 5 | ||||
rs13217519 rs9350276 | ||||
GA | 36.73 | 1 | ||
AA | 35.32 | 1.03 | 0.79-1.33 | 0.845 |
AG | 27.94 | 0.71 | 0.54-0.93 | 0.015 |