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. 2019 Apr 14;2019:8563095. doi: 10.1155/2019/8563095

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Copyright © 2019 Catarina Silvestre et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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(a) FISH analysis depicting two interphase cells. Top: a cell showing only one green signal for the centromeric X region (DXZ1) indicating a 45,X cell; bottom: the cell shows one green signal (DXZ1) and two distinct but proximal red signals for the Y centromeric region (DYZ3) present on the idic (Y) chromosome. (b) FISH analysis using probes for the centromeric X region (DXZ1, green) and for the sex-determining region of Y chromosome on Yp11.3 (SRY, red) on a metaphase spread showing one signal on the chromosome X and one condensed signal on the idic (Y) (arrow) and (c) on interphase cells showing two hybridizations signals for the SRY region in mosaic.