Table 3.
Drug loaded NE formulation composition and physical screening studies.
| Formulation code | Surfactant : co-surfactant ratio | Oil % | Smix% | Water % | Physical Stability test | Inference | |||
|---|---|---|---|---|---|---|---|---|---|
| Heating | Freeze thaw cycle | Centrifugation | |||||||
| F1 | 4:1 | 10 | 32 | 8 | 50 | ✓ | ✓ | ✓ | Passed |
| F5 | 11.94 | 14.33 | 3.58 | 70.15 | - | - | - | Failed | |
| F7 | 11.63 | 18.61 | 4.65 | 65.12 | ✓ | - | - | Failed | |
| F8 | 11.11 | 19.445 | 19.445 | 50 | ✓ | - | - | Failed | |
| F12 | 6.67 | 11.665 | 11.665 | 70 | ✓ | - | - | Failed | |
| F14 | 6.67 | 16.665 | 16.665 | 60 | ✓ | - | - | Failed | |
| F15 | 5.8 | 14.495 | 14.495 | 65.22 | - | - | - | Failed | |
Composition of drug loaded NE and their physical stability testing, F1 gave a clear and transparent formulation.