Table 2.
Body weight of Plasmodium berghei infected mice after administration of the leaf latex and TLC isolates of Aloe megalacantha.
| Test substance | Dose (mg/kg/day) | Wt D0 (g) | Wt D4 (g) | Mean difference |
|---|---|---|---|---|
| NC | 10 ml/kg | 21.9 ± 0.63 | 20.9 ± 0.64 | -1.0 (4.6) |
| Latex | 100 | 23.2 ± 0.48 | 23.1 ± 0.44 | -0.1 (0.4) |
| 200 | 21.4 ± 1.22 | 21.7 ± 1.01 | 0.3 (1.4) | |
| 400 | 20.1 ± 0.23 | 21.2 ± 0.59 | 1.1 (5.5) | |
| AM1 | 100 | 20.6 ± 0.38 | 20.8 ± 0.42 | 0.2 (1.0) |
| 200 | 20.7 ± 0.38 | 21.6 ± 0.32 | 0.9 (4.4) | |
| 400 | 21.1 ± 0.35 | 22.4 ± 0.56 | 1.3 (6.2) | |
| AM2 | 100 | 22.3 ± 0.91 | 22.7 ± 1.03 | 0.2 (0.9) |
| 200 | 21.7 ± 0.67 | 22.8 ± 0.78 | 1.1 (5.1) | |
| 400 | 21.2 ± 0.45 | 22.7 ± 0.28 | 1.5 (7.1) | |
| AM3 | 100 | 20.6 ± 0.48 | 21.8 ± 0.47 | 1.2 (5.8) |
| 200 | 21.9 ± 0.45 | 23.5 ± 0.88 | 1.6 (7.3) | |
| 400 | 21.3 ± 0.46 | 23.3 ± 0.57 | 2.0 (9.4) | |
| CQ | 25 | 21.9 ± 0.38 | 23.2 ± 0.27 | 1.3 (5.9) |
Values are presented as M ± SEM; n refers to number of mice, n = 5; Wt D0: weight before treatment on day zero; Wt D4: weight after treatment on fifth day (day 4); values in parenthesis indicate percent of change.