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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: J Am Coll Surg. 2019 Jan 21;228(5):760–768.e1. doi: 10.1016/j.jamcollsurg.2019.01.009

Table 3.

Multivariate Analysis of the Modification of the Association Between Abnormal Activating Clotting Time, Angle, Maximum Amplitude, and Fibrinolysis with Death, by Sex

Coagulation phenotype Analysis of conditional maximum likelihood estimate Standard error p Value
Abnormal ACT 1.06 0.35 0.003
Abnormal ACT + male sex 0.18 0.32 0.58
Abnormal angle 0.53 0.36 0.14
Abnormal angle + male sex 0.46 0.34 0.18
Abnormal MA 0.32 0.38 0.41
Abnormal MA + male sex 0.74 0.38 0.04
Hyperfibrinolysis 0.85 0.32 0.60
Hyperfibrinolysis + male sex −0.39 0.31 0.21
Fibrinolysis shutdown −0.25 0.33 0.46
Fibrinolysis shutdown + male sex 0.17 0.33 0.60

Abnormal activated clotting time: >128 s; abnormal angle: <65 degrees; Abnormal maximum amplitude: <55 mm; hyperfibrinolysis: LY30 (30 min after maximum amplitude) ≥3%; fibrinolysis shutdown: LY30 <0.9%.

ACT, activated clotting time; MA, maximum amplitude.