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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Mitochondrion. 2019 Mar 26;46:1–5. doi: 10.1016/j.mito.2019.03.001

Fig. 1.

Fig. 1.

Basis of the OMA1 activity using fluorescence-based technology. A) Fluorescence is released when OMA1 recognizes and cleaves the OPA1 8-mer peptide (fluorescence reporter) presumably at the RA site. B) Experimental workflow. [Abbreviations: MCA - 7 Methoxycoumarin 4 ylacetyl; DNP - 2,4 Dinitrophenyl; TPEN - N,N,N′,N′-tetrakis(2-pyridinylmethyl)-1,2-ethanediamine.