Table 2. Correlation of STC2 protein and mRNA expression with clinicopathological features in HCC (N[%]).
| Characteristic | n | STC2 protein positive rate | x2 | P | STC2 mRNA positive rate | x2 | P |
|---|---|---|---|---|---|---|---|
| Gender | |||||||
| Male | 112 | 92 (82.1) | 0.180 | 0.669 | 86 (76.8) | 0.022 | 0.929 |
| Female | 88 | 71 (80.7) | 65 (73.9) | ||||
| Age (years) | |||||||
| <40 | 45 | 37 (82.2) | 0.194 | 0.828 | 35 (77.8) | 0.026 | 0.954 |
| ≥40 | 155 | 126 (81.3) | 116 (74.8) | ||||
| Tumor diameter (cm) | |||||||
| <5 | 84 | 58 (69.05) | 0.165 | 0.009 | 52 (61.90) | 0.108 | 0.012 |
| ≥5 | 116 | 105 (90.51) | 99 (85.34) | ||||
| Number of tumors | |||||||
| 1 | 135 | 111 (82.2) | 0.219 | 0.955 | 103 (76.3) | 0.122 | 0.295 |
| ≥2 | 65 | 52 (80.0) | 48 (73.8) | ||||
| Carcinoma emboli in the portal vein | |||||||
| Yes | 66 | 62 (93.94) | 0.215 | 0.036 | 59 (89.39) | 0.181 | 0.029 |
| No | 134 | 101 (75.37) | 92 (68.66) | ||||
| Combined with cirrhosis | |||||||
| Yes | 123 | 99 (80.5) | 0.230 | 0.369 | 94 (76.4) | 0.122 | 0.628 |
| No | 77 | 64 (85.3) | 57 (74.0) | ||||
| Degree of tumor differentiation | |||||||
| High and moderate differentiation | 35 | 16 (45.71) | 0.251 | 0.003 | 13 (37.14) | 0.234 | 0.004 |
| Poor differentiation | 165 | 147 (89.09) | 138 (83.64) | ||||
| Tumor metastasis | |||||||
| Yes | 56 | 52 (92.86) | 0.234 | 0.041 | 49 (87.50) | 0.198 | 0.031 |
| No | 144 | 112 (77.78) | 102 (70.83) | ||||
| Tumor stage | |||||||
| I–II | 51 | 31 (60.78) | 7.543 | 0.006 | 29 (56.86) | 7.122 | 0.007 |
| III–IV | 149 | 132 (88.59) | 122 (81.88) | ||||