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. 2019 Apr 28;25(16):1950–1963. doi: 10.3748/wjg.v25.i16.1950

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©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Phenotypes of NK cells in different clinical phases. A: Frequency of CD56^bright and CD56^dim NK cells expressing the activating receptor NKp46; B: Frequency of CD56^bright and CD56^dim NK cells expressing the activating receptor NKp44; C: Frequency of CD56^bright and CD56^dim NK cells expressing the activating receptor NKp30; D: Frequency of CD56^bright and CD56^dim NK cells expressing the inhibitory receptor NKG2A; E: Frequency of CD56^bright and CD56^dim NK cells expressing the activating receptor NKG2D; F: Frequency of CD56^bright and CD56^dim NK cells expressing the activating marker CD69. NK: Natural killer; HD: Healthy honors; IT: Immune tolerant; IA: Immune active; IC: Inactive carrier; ENEG: Hepatitis B envelope antigen-negative hepatitis. All data are presented as mean ± SD, ^aP < 0.05, ^bP < 0.01, ^cP < 0.001.