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. 2019 Apr 29;2019(4):CD001808. doi: 10.1002/14651858.CD001808.pub3

Comparison 3. Oxytocin versus ergot alkaloids.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Blood loss 500 mL or more after delivery 10 3082 Risk Ratio (M‐H, Random, 95% CI) 0.84 [0.56, 1.25]
2 Need for additional uterotonics 8 2178 Risk Ratio (M‐H, Random, 95% CI) 0.89 [0.43, 1.81]
3 Blood loss 1000 mL or more after delivery 3 1577 Risk Ratio (M‐H, Fixed, 95% CI) 1.13 [0.63, 2.01]
4 Blood transfusion 7 1578 Risk Ratio (M‐H, Random, 95% CI) 1.37 [0.34, 5.51]
5 Third stage > 30 minutes 2 450 Risk Ratio (M‐H, Fixed, 95% CI) 4.69 [1.63, 13.45]
6 Diastolic blood pressure > 100 mm Hg between delivery of the baby and discharge from the labour ward 3 960 Risk Ratio (M‐H, Random, 95% CI) 0.28 [0.04, 2.05]
7 Mean blood loss (mL) 11 3598 Mean Difference (IV, Random, 95% CI) ‐13.97 [‐43.70, 15.76]
8 Mean length of third stage (minutes) 8 2892 Mean Difference (IV, Random, 95% CI) 0.09 [‐0.44, 0.61]
9 Manual removal of the placenta 8 3127 Risk Ratio (M‐H, Random, 95% CI) 1.10 [0.39, 3.10]
10 Vomiting between delivery of the baby and discharge from the labour ward 7 1991 Risk Ratio (M‐H, Fixed, 95% CI) 0.09 [0.05, 0.14]
11 Headaches between delivery of the baby and discharge from the labour ward 5 1543 Risk Ratio (M‐H, Random, 95% CI) 0.19 [0.03, 1.02]