Saito 2007.

Methods	Quasi randomised: quote: "...women were allocated to a group in a temporal manner (...) selected weekly or monthly, as determined by each hospital, in alternate shifts".
Participants	343 consenting women with low risk of PPH at 4 hospitals in Japan Excluded: contraindication for ergometrine, multiple pregnancies, non‐cephalic presentation, uterine fibroids or deformity, placenta previa, history of PPH, parity > 4, previous caesarean section, severe anaemia, pre‐eclampsia, epidural anaesthesia, use of oxytocics, anticoagulation therapy, estimated baby weight < 2000 g or > 4000 g.
Interventions	Shortly after delivery of the baby: A. oxytocin 5 IU IM (n = 156); B. methylergometrine 0.2 mg IM (n = 187). AMTSL in both groups. immediate cord clamping and cutting, controlled cord traction. Blood loss was calculated objectively by measuring the amount of collected blood and by the weighting of surgical sponges, clothes and drapes by experienced attending midwives who were not involved in the administration of prophylactic oxytocics.
Outcomes	Blood loss (mL), maternal blood pressure, nausea, vomiting, headache, chest pain, dyspnoea, duration of the third stage (minutes), additional uterotonics, blood transfusion, manual placental removal.
Notes	Dates of study: September 2000 – April 2002 Funding sources: not reported Declarations of interest: not reported
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	High risk	Quasi random: quote: "...women were allocated to a group in a temporal manner (...) selected weekly or monthly, as determined by each hospital, in alternate shifts.".
Allocation concealment (selection bias)	High risk	Inadequate. quote: "...women were allocated to a group in a temporal manner (...) selected weekly or monthly, as determined by each hospital, in alternate shifts."
Blinding of participants and personnel (performance bias) All outcomes	High risk	Not blinded.
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Not blinded, but quote: “Blood loss was calculated objectively by measuring the amount of collected blood and by the weighing of surgical sponges, clothes and drapes by experienced attending midwives who were not involved in the administration of prophylactic oxytocics.”
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	It is not possible to know from the study report how many women were originally randomised.
Selective reporting (reporting bias)	Unclear risk	Protocol unseen. No outcomes were pre‐specified in methods with the exception of estimated blood loss.
Other bias	Unclear risk	Unclear.