Study	Reason for exclusion
Barbaro 1961	No randomisation of treatment groups.
Boucher 2004	Comparison of intramuscular carbetocin to a 2‐hour IV oxytocin infusion administered after delivery of the placenta.
Dickinson 2009	Comparison of oxytocin, misoprostol and no additional medication for the third‐stage management after second trimester medical termination.
Docherty 1981	Oxytocin vs ergometrine‐oxytocin (subject of separate review).
Dommisse 1980	No randomisation of treatment groups.
Dumoulin 1981	Oxytocin (different doses) vs ergometrine‐oxytocin (subject of separate review).
Friedman 1957	Likely to be considerable bias after entry to study as 27% of the 1221 were 'deleted from the study' as inadequate observations were obtained. No other reasons given, and no indication of whether these women were missing in similar proportions from the 5 intervention groups.
Gerstenfeld 2001	Comparison of oxytocin with misoprostol (subject of separate review).
Hacker 1979	No randomisation of treatment groups.
Hoffman 2006b	Comparison of oxytocin within the context of active vs expectant management (subject of a separate review).
Howard 1964	Oxytocin, methergine or placebo given after delivery of the placenta.
Huh 2000	Excluded as only different timing of administration.
Irons 1994	Comparison of nipple stimulation to ergometrine‐oxytocin which is not a subject of this review.
Jackson 2001	Comparison of oxytocin administered before and after placental delivery so the only difference is timing of administration.
Jans 2017	Comparison of oxytocin to expectant management without placebo.
Khan 1997	Comparison of prophylactic oxytocin within context of active management vs oxytocin after placental delivery within context of expectant management (subject of separate review by Begley et al: Active versus expectant management of third stage of labour ‐ seeBegley 2019).
Kundodyiwa 2001	Comparison of oxytocin with misoprostol (subject of separate review).
Lokugamage 2001	Comparison of oxytocin to misoprostol (subject of separate review) and at caesarean section.
Muller 1996	5 IU IV oxytocin with crowning of head and Brandt‐Andrews vs expectant. Abstract only, in French and German. No clinical data available from authors.
Neri‐Mejia 2016	Comparison of various oxytocin routes of delivery without a placebo group.
Newton 1961	Oxytocin or placebo given after delivery of the placenta.
Nieminen 1963	No randomisation of treatment groups.
Nuamsiri 2016	Comparison of oxytocin plus ergometrine to oxytocin alone.
Oguz Orhan 2014	Comparison of different routes and timing of oxytocin administration.
Parsons 2004	Comparison of oxytocin with misoprostol (subject of separate review).
Porter 1991	Comparison of different routes of administration of oxytocin.
Quibel 2016	Comparison of oxytocin and misoprostol to oxytocin.
Ramirez 2001	Inadequate information available about randomisation and available only as abstract.
Rouse 2011	Comparison between different doses of oxytocin without placebo or alternate uterotonic.
Sariganont 1999	No randomisation of treatment groups.
Schaefer 2004	Excluded as only difference is timing of administration.
Schemmer 2001	Comparison of oxytocin administered before and after placental delivery so the only difference is timing of administration.
Sharma 2014	Treatment groups were not randomised.
Soiva 1964	Trial includes a large group of women who were not randomised (data were collected retrospectively) and whose outcome data are inseparable from those that were randomised.
Soriano 1995	Compares oxytocin with oxytocin plus ergometrine (subject of separate review).
Stanton 2010	Study withdrawn due to lack of IRB approval.
Stanton 2012	Manuscript published is of study protocol only, data planned to be analysed in 2013.
Stanton 2013	Comparison groups outside scope of this review.
Stearn 1963	Allocation was to 2 different consultants, 1 of whom gave all patients ergometrine‐oxytocin, and the other to give 'normal' cases ergometrine with hyalase and abnormal given IV ergometrine.
Suhrabi 2013	Comparison groups outside scope of this review.
Sunil 2016	Comparison of oxytocin to carboprost.
Symes 1984	Compares oxytocin with oxytocin plus ergometrine (subject of separate review).
Tessier 2000	Excluded as only different routes of administration.
Thornton 1988	Strong likelihood of post‐entry bias as alternate allocation used for 65, but 40 were withdrawn 40 as did not meet inclusion criteria, leaving 10 and 15 in trial comparing oxytocin vs no oxytocin within active management. Primary outcome plasma oxytocin concentration.
Tita 2012	Comparison between different doses of oxytocin without placebo or alternate uterotonic.
Vasegh 2005	Comparison of active vs expectant management of the third stage of labour (subject of a separate review). Study design information not available.
Yuen 1995	Oxytocin vs ergometrine‐oxytocin (subject of separate review).

IRB: Institutional Review Board
 IU: international unit
 IV: intravenous
 vs: versus