Table 1.

Apparent permeability coefficient (P _app ) of REG, across everted gut sacs at various drug concentrations (Mean ± SD, n = 3)

Concentration (µM)	P app × 10 -5 (cm/s)
10	1.21 ± 0.14
20	1.16 ± 0.09
40	1.23 ± 0.19
100	3.29 ± 0.58**

^** P < 0.01: significant difference when compared to the lower REG lower concentrations.