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. 2019 Winter;18(1):296–307.

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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effect of OXT administration on the activity of CAT and SOD enzymes in different brain regions of 3-NP injected male rats. 3-NP reduced the activity of the CAT in different brain regions but interesting, OXT improved its activity in all areas studied in male rats (a, c, e and g). Reduction of activity of the SOD, which was caused by toxin injection, was also improved by OXT in different areas of male rats (b, d, f and h). Data are presented as means ± SEM (n = 6/group). ****p < 0.0001 compared with the Control; #p < 0.05, ##p < 0.01 and ####p < 0.0001 compared between the 3-NP and 3-NP-OXT groups. OXT: oxytocin; 3-NP: 3-Nitropropionic acid; CAT: catalase; SOD: superoxide dismutase