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. 2019 Winter;18(1):241–253.

Figure 2.

Effect of Halobacterium salinarum IBRC M10715 supernatant metabolite on apoptosis of prostate cancer cell lines (DU145 and PC3). (A) Apoptosis test of Halobacterium salinarum SM on DU145 and PC3 cells was done by annexin-PI staining, two days post treatment. Downright quadrate shows cells in early apoptosis and upright quadrate shows late apoptosis. (B) The comparison of early apoptosis and (C) late apoptosis in both DU145 and PC3 cells post 48 h treatment with 0.5 mg/mL of Halobacterium salinarum SM.

Figure 2

(D) Quantitative real-time PCR analysis of CASP3, as marker of late apoptosis, after 48 h treatment with 0.5 mg/mL of Halobacterium salinarum SM in PC3 and DU145. *p < 0.05, ***p < 0.001.