Table 1.A.
Demographics of ADNI participants stratified by baseline diagnosisa.
| Variable | N | CN (N=370) |
EMCI (N=284) |
LMCI (N=505) |
AD (N=305) |
p-valueb |
|---|---|---|---|---|---|---|
| Age | 1464 | 74.58(5.71) | 71.12(7.51) | 73.95(7.59) | 74.70(7.79) | P<0.001 |
| Sex: Female, No. (%) | 1464 | 190(51%) | 130(46%) | 197(39%) | 139(46%) | P=0.004 |
| Education, years | 1464 | 16.28(2.92) | 15.95(2.66) | 15.87(2.90) | 15.16(3.00) | P<0.001 |
| BMI (Kg/M2) | 1461 | 27.05(4.46) | 28.06(5.41) | 26.54(4.25) | 25.83(4.69) | P<0.001 |
| ≥1APOE ε4 allele, No.(%) | 1464 | 104(28%) | 121(43%) | 273(54%) | 202(66%) | P<0.001 |
| ADAS-Cog13c | 1455 | 9.19(4.17) | 12.64(5.40) | 18.67(6.62) | 29.67(8.20) | P<0.001 |
a
Data are reported as mean(SD) unless otherwise indicated. Bolded values indicate statistical significance. SD: Standard deviation.
b
Based on 2-sample t tests, or Pearson χ2 tests.
c
Score explanations: ADAS-Cog13 range, 0 (best) to 85 (worst).
Abbreviations: AD: Alzheimer’s disease; BMI: Body mass index; CN: Cognitively normal; EMCI: Early mild cognitive impairment; LMCI: Late mild cognitive impairment; ADAS-Cog13, Alzheimer Disease Assessment Scale 13-item cognitive subscale.