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. Author manuscript; available in PMC: 2019 Oct 17.
Published in final edited form as: Vaccine. 2019 Mar 25;37(17):2377–2386. doi: 10.1016/j.vaccine.2019.03.007

Table 1.

Measles cases, costs ($US), and DALYs averted through outreach vaccination when 25% of geographically hard-to reach children are included in catchment areas of proposed outreach vaccination sessions, Kenya 2016–2020.

Fixed vaccination posts catchment radius Proportion of target population vaccinated within fixed post catchments* Proportion of hard-to-reach target population vaccinated* Proportion of total target population vaccinated* Measles cases averted Deaths averted DALYs averted Direct medical costs averted Productivity losses averted Total societal costs averted Outreach vaccination strategy costs
25% of Population that Received MCV1 Receives MCV2
2.5 MCV1: 100% MCV1: 25% MCV1: 61% 22,699 4086 119,399 617,653 150,497,104 151,114,757 583,866
MCV2: 25% MCV2: 6% MCV2: 15% (21,161–22,734) (1693–9321) (49,518–228,934) (266,422–1,098,063) (45,093,474–285,685,096) (45,359,896–286,783,159) (219,641–984,953)
5 MCV1: 100% MCV1: 25% MCV1: 84% 2247 404 11,818 61,135 14,896,019 14,957,154 264,027
MCV2: 25% MCV2: 6% MCV2: 21% (2234–2306) (179–9450) (5227–23,217) (28,124–111,357) (4,760,108–27,371,447) (4,788,231–27,482,804) (94,140–457,439)
10 MCV1: 100% MCV1: 25% MCV1: 95% 22 <5 116 601 146,389 146,989 130,790
MCV2: 25% MCV2: 6% MCV2: 24% (28–18) (65–184) (352–882) (229,422–229,422) (230,304–230,304) (37,849–242,704)
 
50% of Population that Received MCV1 Receives MCV2
2.5 MCV1: 100% MCV1: 25% MCV1: 61% 23,234 4182 122,213 632,210 154,044,054 154,676,264 700,639
MCV2: 50% MCV2: 13% MCV2: 31% (21,806–24,194) (1,744–9920) (51,027–243,631) (274,543–1,168,558) (46,467,920–304,025,953) (46,742,463–305,194,511) (263,569–1,181,943)
5 MCV1: 100% MCV1: 25% MCV1: 84% 747 134 3927 20,313 4,949,355 4,969,667 316,832
MCV2: 50% MCV2: 13% MCV2: 42% (752–758) (60–311) (1759–7633) (9466–36,612) (1,602,250–8,999,175) (1,611,717–9,035,787) (112,968–548,927)
10 MCV1: 100% MCV1: 25% MCV1: 95% 23 <5 119 616 150,211 150,827 156,948
MCV2: 50% MCV2: 13% MCV2: 47% (30–29) (69–293) (372–1405) (365,669–365,669) (367,074–367,074) (45,419–291,245)
 
75% of Population that Received MCV1 Receives MCV2
2.5 MCV1: 100% MCV1: 25% MCV1: 61% 26,505 4771 139,416 721,197 175,726,729 176,447,927 817,413
MCV2: 75% MCV2: 19% MCV2: 46% (25,662–26,135) (2038–10,867) (60,048–263,177) (323,080–1,262,309) (56,575,100–328,417,316) (56,898,180–329,679,626) (307,497–1,378,934)
5 MCV1: 100% MCV1: 25% MCV1: 84% 217 39 1143 5913 1,440,702 1,446,615 369,638
MCV2: 75% MCV2: 19% MCV2: 63% (242–226) (17–99) (566–2281) (3045–10,939) (515,453–2,688,855) (518,498–2,699,794) (131,797–640,415)
10 MCV1: 100% MCV1: 25% MCV1: 95% 22 <5 115 596 145,279 145,875 183,106
MCV2: 75% MCV2: 19% MCV2: 71% (24–27) (56–275) (304–1318) (342,906–342,906) (344,224–344,224) (52,989–339,786)
 
100% of Population that Received MCV1 Receives MCV2
2.5 MCV1: 100% MCV1: 25% MCV1: 61% 25,806 4645 135,739 702,180 171,093,010 171,795,190 934,186
MCV2: 100% MCV2: 25% MCV2: 61% (25,424–25,923) (2034–10,780) (59,493–261,047) (320,093–1,252,093) (54,177,661–325,759,373) (54,497,754–327,011,466) (351,426–1,575,924)
5 MCV1: 100% MCV1: 25% MCV1: 84% 92 17 482 2494 607,660 610,154 422,443
MCV2: 100% MCV2: 25% MCV2: 84% (83–97) (7–40) (195–981) (1050–4707) (177,700–1,156,867) (178,750–1,161,573) (150,625–731,903)
10 MCV1: 100% MCV1: 25% MCV1: 95% 26 <5 138 713 173,712 174,425 209,264
MCV2: 100% MCV2: 25% MCV2: 95% (24–22) (55–226) (297–1086) (282,621–282,621) (283,707–283,707) (60,559–388,327)
*

MCV1 = first dose of measles-containing vaccine; MCV2 = second dose of measles-containing vaccine; MCV1 target population = eligible children <12 months (i.e., surviving infants); MCV2 target population = eligible children 12–23 months;

Values are rounded to nearest whole number and cannot be used to reconstruct incremental cost-effectiveness ratios (ICERs) reported in the text, which used unrounded values. Note: Base value correspond to an outreach vaccination location catchment area radius of 10 km. Ranges represent the minimum and maximum values when varying parameters across their ranges, for an outreach vaccination location catchment area radius of 7.5–20 km. Logistics cost assumes a child is vaccinated every 15 min(2–30 min).