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. Author manuscript; available in PMC: 2019 Oct 17.
Published in final edited form as: Vaccine. 2019 Mar 25;37(17):2377–2386. doi: 10.1016/j.vaccine.2019.03.007

Table 2.

Measles cases, costs ($US), and DALYs averted through outreach vaccination when 50% of geographically hard-to reach children are included in catchment areas of proposed outreach vaccination sessions, Kenya 2016–2020.

Fixed vaccination posts catchment radius Proportion of target population vaccinated within fixed post catchments* Proportion of hard-to-reach target population vaccinated* Proportion of total target population vaccinated* Measles cases averted Deaths averted DALYs averted Direct medical costs averted Productivity losses averted Total societal costs averted Outreach vaccination strategy costs
25% of Population that Received MCV! Receives MCV2
2.5 MCV1: 100% MCV1: 50% MCV1: 74% 43,858 7894 230,694 1,193,382 290,778,977 291,972,358 1,153,637
MCV2: 25% MCV2: 13% MCV2: 19% (43,742–43,929) (3,463–18,011) (102,355–442,365) (550,706–2,121,772) (93,210,173–552,025,216) (93,760,879–554,146,987) (439,591–1,955,085)
5 MCV1: 100% MCV1: 50% MCV1: 90% 2877 518 15,133 78,285 19,074,967 19,153,252 521,940
MCV2: 25% MCV2: 13% MCV2: 22% (2852–2863) (228–1189) (6673–28,834) (35,901–138,301) (6,076,371–33,994,263) (6,112,272–34,132,564) (187,397–891,469)
10 MCV1: 100% MCV1: 50% MCV1: 97% 55 10 290 1499 365,291 366,791 266,949
MCV2: 25% MCV2: 13% MCV2: 24% (49–40) (3–23) (115–405) (617–1941) (504,891–504,891) (506,831–506,831) (79,432–497,655)
 
50% of Population that Received MCVI Receives MCV2
2.5 MCV1: 100% MCV1: 50% MCV1: 74% 42,246 7604 222,212 1,149,501 280,087,153 281,236,654 1,384,364
MCV2: 50% MCV2: 25% MCV2: 37% (42,366–42,404) (3380–17,431) (99,136–427,009) (533,383–2,048,117) (90,278,170–532,862,383) (90,811,553–534,910,500) (527,509–2,346,102)
5 MCV1: 100% MCV1: 50% MCV1: 90% 938 169 4934 25,523 6,218,811 6,244,333 626,328
MCV2: 50% MCV2: 25% MCV2: 45% (938–934) (75–388) (2196–9405) (11,815–45,109) (1,999,720–11,087,687) (2,011,535–11,132,796) (224,876–1,069,763)
10 MCV1: 100% MCV1: 50% MCV1: 97% 34 6 177 917 223,347 224,264 320,339
MCV2: 50% MCV2: 25% MCV2: 48% (29–38) (2–16) (68–380) (368–1821) (473,834–473,834) (475,656–475,656) (95,319–597,187)
 
75% of Population that Received MCVI Receives MCV2
2.5 MCV1: 100% MCV1: 50% MCV1: 74% 41,620 7492 218,923 1,132,490 275,942,065 277,074,554 1,615,092
MCV2: 75% MCV2: 38% MCV2: 56% (41,587–41,538) (3323–17,064) (97,313–418,286) (523,578–2,006,276) (88,618,544–521,976,488) (89,142,122–523,982,763) (615,427–2,737,119)
5 MCV1: 100% MCV1: 50% MCV1: 90% 313 56 1647 8519 2,075,659 2,084,178 730,716
MCV2: 75% MCV2: 38% MCV2: 67% (319–313) (25–131) (746–3153) (4013–15,121) (679,144–3,716,806) (683,157–3,731,927) (262,356–1,328,667)
10 MCV1: 100% MCV1: 50% MCV1: 97% 33 6 171 886 215,862 216,748 373,729
MCV2: 75% MCV2: 38% MCV2: 72% (37–36) (2–15) (87–367) (468–1762) (458,382–458,382) (460,144–460,144) (111,205–696,718)
 
100% of Population that Received MCVl Receives MCV2
2.5 MCV1: 100% MCV1: 50% MCV1: 74% 37,489 6748 197,192 1,020,077 248,551,653 249,571,730 1,845,819
MCV2: 100% MCV2: 50% MCV2: 74% (37,513–37,466) (2997–15,380) (87,781–377,282) (472,294–1,809,603) (79,938,493–470,807,872) (80,410,787–472,617,476) (703,346–3,128,136)
5 MCV1: 100% MCV1: 50% MCV1: 90% 163 29 859 4446 1,083,204 1,087,650 835,104
MCV2: 100% MCV2: 50% MCV2: 90% (163–160) (13–67) (382–1612) (2057–7731) (348,156–1,900,251) (350,213–1,907,981) (299,835–1,426,351)
10 MCV1: 100% MCV1: 50% MCV1: 97% 33 6 171 886 215,888 216,774 427,119
MCV2: 100% MCV2: 50% MCV2: 97% (28–27) (2–14) (64–270) (347–1293) (336,361–336,361) (337,654–337,654) (127,092–796,249)
*

MCV1 = first dose of measles-containing vaccine; MCV2 = second dose of measles-containing vaccine; MCV1 target population = eligible children < 12 months (i.e., surviving infants); MCV2 target population = eligible children 12–23 months;

Values are rounded to nearest whole number and cannot be used to reconstruct incremental cost-effectiveness ratios (ICERs) reported in the text, which used unrounded values. Note: Base value correspond to an outreach vaccination location catchment area radius of 10 km. Ranges represent the minimum and maximum values when varying parameters across their ranges, for an outreach vaccination location catchment area radius of 7.5–20 km. Logistics cost assumes a child is vaccinated every 15 min (2–30 min).